GK104 ScienCell 人類細(xì)胞骨架重塑qPCR檢測試劑盒，Human Cytoskeletal Remodeling qPCR Array Kit

ScienCell 研究實驗室（ScienCell）是一家生物技術(shù)公司，其使命是實驗和治療用細(xì)胞和細(xì)胞相關(guān)產(chǎn)品的研究和發(fā)展。 ScienCell為研究界提供各種高質(zhì)量的正常的人類和動物細(xì)胞，細(xì)胞培養(yǎng)基和試劑，培養(yǎng)基添加因子，細(xì)胞來源的RNA，cDNA和蛋白質(zhì)。ScienCell的科學(xué)家們以改善生活質(zhì)量，實現(xiàn)細(xì)胞的能力，打擊人類退化性疾病為目的研究和開發(fā)各種細(xì)胞治療策略。ScienCell總部設(shè)在美國加利福尼亞州圣地亞哥，公司成立于1999年。

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GK104 ScienCell人類細(xì)胞骨架重塑qPCR檢測試劑盒，Human Cytoskeletal Remodeling qPCR Array Kit，產(chǎn)品簡介：

產(chǎn)品品牌： ScienCell

產(chǎn)品貨號：GK104

產(chǎn)品名稱：GK104 ScienCell人類細(xì)胞骨架重塑qPCR檢測試劑盒，Human Cytoskeletal Remodeling qPCR Array Kit

產(chǎn)品規(guī)格：One 96-well plate, one 20ul reaction per well

GK104 ScienCell人類細(xì)胞骨架重塑qPCR檢測試劑盒，Human Cytoskeletal Remodeling qPCR Array Kit， 產(chǎn)品說明：

ScienCell的GeneQuery™人類細(xì)胞骨架重塑qPCR陣列試劑盒（GQH-CYT）分析了參與細(xì)胞骨架重塑的88個關(guān)鍵基因，特別關(guān)注Rho GTP酶肌動蛋白細(xì)胞骨架重塑。 細(xì)胞骨架負(fù)責(zé)維持細(xì)胞形狀、支架和調(diào)節(jié)細(xì)胞內(nèi)運(yùn)輸。 它還參與許多信號通路、細(xì)胞分裂、囊泡運(yùn)輸和運(yùn)動。 微絲主要是肌動蛋白聚合物，是細(xì)胞骨架的一部分，由GTP酶Rho家族調(diào)節(jié)。 如何對所包含的基因進(jìn)行分類的簡要示例如下所示：

細(xì)胞骨架成分：ACTA1、ACTB、ACTG1、ACTN1、MYH10、MYL1

整合素： ITGA1， ITGA3， ITGAV， ITGB1， ITGB3

細(xì)胞外基質(zhì)成分：COL1A1，COL2A1，COL4A1，LAMA1，LAMB1

Rho信號分子：CAV1，CDC42，RAC1，RHOA，ROCK1，ROCK2

轉(zhuǎn)錄因子：CDX1、CDX2、SP1、TCF7、TCF7L1

GeneQuery™ qPCR 芯片試劑盒采用 96 孔板格式的 qPCR 就緒，每個孔包含一個引物組，可識別并有效擴(kuò)增特定靶基因的 cDNA。精心設(shè)計的引物確保：（i）qPCR分析中的優(yōu)良退火溫度為65°C（含2 mM Mg2+且不含DMSO）;（ii）除非另有說明，否則引物集可識別靶基因的所有已知轉(zhuǎn)錄本變體;（iii）只有一個基因被擴(kuò)增。每個引物組都已通過qPCR和熔解曲線分析和凝膠電泳進(jìn)行了驗證。

ScienCell's GeneQuery™ Human Cytoskeletal Remodeling qPCR Array Kit (GQH-CYT) profiles 88 key genes involved in cytoskeletal remodeling with a particular focus on Rho GTPase actin cytoskeleton remodeling.  The cytoskeleton is responsible for maintaining cell shape, scaffolding, and regulating intracellular transport.  It is also involved in numerous signaling pathways, cellular division, vesicular trafficking, and motility.  Microfilaments, which are primarily actin polymers, are part of the cytoskeleton and regulated by the Rho family of GTPases.  Brief examples of how included genes may be categorized are shown below:

·         Cytoskeletal components: ACTA1, ACTB, ACTG1, ACTN1, MYH10, MYL1

·         Integrins: ITGA1, ITGA3, ITGAV, ITGB1, ITGB3

·         Extracellular matrix components: COL1A1, COL2A1, COL4A1, LAMA1, LAMB1

·         Rho signaling molecules: CAV1, CDC42, RAC1, RHOA, ROCK1, ROCK2

·         Transcription factors: CDX1, CDX2, SP1, TCF7, TCF7L1

GeneQuery™ qPCR array kits are qPCR ready in a 96-well plate format, with each well containing one primer set that recognizes and efficiently amplifies a specific target gene's cDNA. The carefully designed primers ensure that: (i) the optimal annealing temperature in qPCR analysis is 65°C (with 2 mM Mg2+and no DMSO); (ii) the primer set recognizes all known transcript variants of the target gene, unless otherwise noted; and (iii) only one gene is amplified. Each primer set has been validated by qPCR with melt curve analysis and gel electrophoresis.

GeneQuery™ 人類細(xì)胞骨架重塑 qPCR 陣列板布局*（8 個粗體和斜體對照）

提示：基因選擇可能會根據(jù)新的研究和開發(fā)進(jìn)行更新

ScienCell基因表達(dá)分析產(chǎn)品訂購信息：

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GK006   人類神經(jīng)發(fā)育和再生qPCR檢測試劑盒，Human Neural Development and Regeneration qPCR Array Kit

GK007   人類神經(jīng)可塑性qPCR檢測試劑盒，Human Neural Plasticity qPCR Array Kit

GK008   人類神經(jīng)傳遞和膜轉(zhuǎn)運(yùn)qPCR檢測試劑盒，Human Neural Transmission and Membrane Trafficking qPCR Array Kit

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GK010   人類黑素細(xì)胞發(fā)育和色素沉著qPCR檢測試劑盒，Human Melanocyte Development & Pigmentation qPCR Array Kit

GK011   人類黑素細(xì)胞生物學(xué)qPCR檢測試劑盒，Human Melanocyte Cell Biology qPCR Array Kit

GK013   人類星型膠質(zhì)細(xì)胞轉(zhuǎn)錄因子qPCR檢測試劑盒，Human Astrocyte Transcription Factors qPCR Array Kit

GK017   人血管生成qPCR檢測試劑盒，Human Angiogenesis qPCR Array Kit

GK018   人內(nèi)皮細(xì)胞表型異質(zhì)性qPCR檢測試劑盒，Human Endothelial Cell Phenotypic Heterogeneity qPCR Array Kit

GK019   人內(nèi)皮細(xì)胞生物學(xué)qPCR檢測試劑盒，Human Endothelial Cell Biology qPCR Array Kit

GK020   人B細(xì)胞受體信號通路qPCR檢測試劑盒，Human B Cell Receptor Signaling Pathway qPCR Array Kit

GK021   人類T細(xì)胞受體信號通路qPCR檢測試劑盒，Human T Cell Receptor Signaling Pathway qPCR Array Kit

GK022   人內(nèi)吞作用qPCR檢測試劑盒，Human Endocytosis qPCR Array Kit

GK023   人皮內(nèi)細(xì)胞分化qPCR檢測試劑盒，Human Endothelial Cell Differentiation qPCR Array Kit

GK024   人體剪切應(yīng)力和機(jī)械傳導(dǎo)qPCR檢測試劑盒，Human Shear Stress and Mechanotransduction qPCR Array Kit

GK025   人類Notch信號通路qPCR檢測試劑盒，uman Notch Signaling Pathway qPCR Array Kit

GK026   人類Wnt信號通路qPCR檢測試劑盒，Human Wnt Signaling Pathway qPCR Array Kit

GK027   人類非經(jīng)典Wnt信號通路qPCR檢測試劑盒，Human Noncanonical Wnt Signaling Pathways qPCR Array Kit

GK028   人類Wnt信號靶基因qPCR檢測試劑盒，Human Wnt Signaling Target Genes qPCR Array Kit

GK029   Human Tie2/Angpt信號qPCR檢測試劑盒，Human Tie2/Angpt Signaling qPCR Array Kit

GK034   人肺纖維化qPCR檢測試劑盒，Human Pulmonary Fibrosis qPCR Array Kit

GK035   人體缺氧反應(yīng)qPCR檢測試劑盒，Human Hypoxia Response qPCR Array Kit

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GK056   人體止血qPCR檢測試劑盒，Human Hemostasis qPCR Array Kit

GK060   人類晝夜節(jié)律qPCR檢測試劑盒，Human Circadian Rhythm qPCR Array Kit

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GK062   人類細(xì)胞生長和分裂qPCR檢測試劑盒，Human Cell Growth and Division qPCR Array Kit

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GK073   人類小膠質(zhì)細(xì)胞Sensome qPCR檢測試劑盒，Human Microglial Sensome qPCR Array Kit

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GK078   人類神經(jīng)細(xì)胞生物學(xué)qPCR檢測試劑盒，Human Neuronal Cell Biology qPCR Array Kit

GK079   人類軟骨細(xì)胞生物學(xué)qPCR檢測試劑盒，Human Chondrocyte Biology qPCR Array Kit

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GK089   人類Ephrin信號qPCR檢測試劑盒，Human Ephrin Signaling qPCR Array Kit

GK090   人體細(xì)胞連接qPCR檢測試劑盒，Human Cell Junctions qPCR Array Kit

GK091   人肝星狀細(xì)胞生物學(xué)qPCR檢測試劑盒，Human Hepatic Stellate Cell Biology qPCR Array Kit

GK092   人胰腺星狀細(xì)胞生物學(xué)qPCR檢測試劑盒，Human Pancreatic Stellate Cell Biology qPCR Array Kit

GK093   Human Renal Mesangial Cell Biology qPCR Array Kit，Human Renal Mesangial Cell Biology qPCR Array Kit

GK094   Human Mesenchymal Stem Cell Differentiation qPCR Array，Human Mesenchymal Stem Cell Differentiation qPCR Array Kit

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GK096   人類雪旺細(xì)胞生物學(xué)qPCR檢測試劑盒，Human Schwann Cell Biology qPCR Array Kit

GK097   人類平滑肌細(xì)胞生物學(xué)qPCR檢測試劑盒，Human Smooth Muscle Cell Biology qPCR Array Kit

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GK099   人類骨骼肌細(xì)胞生物學(xué)qPCR檢測試劑盒，Human Skeletal Muscle Cell Biology qPCR Array Kit

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GK105   人類ECM降解qPCR檢測試劑盒，Human ECM Degradation qPCR Array Kit

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GK124   人類轉(zhuǎn)錄因子qPCR檢測試劑盒，Human Transcription Factors qPCR Array Kit

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