GK088 ScienCell 人VEGF信號(hào)通路qPCR檢測試劑盒，Human VEGF Signaling Pathway qPCR Array Kit

ScienCell 研究實(shí)驗(yàn)室（ScienCell）是一家生物技術(shù)公司，其使命是實(shí)驗(yàn)和治療用細(xì)胞和細(xì)胞相關(guān)產(chǎn)品的研究和發(fā)展。 ScienCell為研究界提供各種高質(zhì)量的正常的人類和動(dòng)物細(xì)胞，細(xì)胞培養(yǎng)基和試劑，培養(yǎng)基添加因子，細(xì)胞來源的RNA，cDNA和蛋白質(zhì)。ScienCell的科學(xué)家們以改善生活質(zhì)量，實(shí)現(xiàn)細(xì)胞的能力，打擊人類退化性疾病為目的研究和開發(fā)各種細(xì)胞治療策略。ScienCell總部設(shè)在美國加利福尼亞州圣地亞哥，公司成立于1999年。

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GK088 ScienCell人VEGF信號(hào)通路qPCR檢測試劑盒，Human VEGF Signaling Pathway qPCR Array Kit，產(chǎn)品簡介：

產(chǎn)品品牌： ScienCell

產(chǎn)品貨號(hào)：GK088

產(chǎn)品名稱：GK088 ScienCell人VEGF信號(hào)通路qPCR檢測試劑盒，Human VEGF Signaling Pathway qPCR Array Kit

產(chǎn)品規(guī)格：One 96-well plate, one 20ul reaction per well

GK088 ScienCell人VEGF信號(hào)通路qPCR檢測試劑盒，Human VEGF Signaling Pathway qPCR Array Kit， 產(chǎn)品說明：

ScienCell的GeneQuery™人類信號(hào)通路qPCR陣列試劑盒（GQH-VEG）分析了參與VEGF和VEGF相關(guān)信號(hào)傳導(dǎo)的88個(gè)關(guān)鍵基因。 VEGF是一種生長因子，以刺激血管生成和血管生成而聞名。 因此，它是發(fā)育、維護(hù)和傷口愈合過程中適當(dāng)血管系統(tǒng)形成bukehuoque的一部分。 異常 VEGF 信號(hào)傳導(dǎo)與缺血、糖尿病視網(wǎng)膜病變、黃斑變性和實(shí)體瘤進(jìn)展有關(guān)。 如何根據(jù)其功能對(duì)所包含的基因進(jìn)行分組的簡要示例如下所示：

信號(hào)受體：FLT1，FLT4，KDR，KIT，FGFR1

生長因子配體：VEGFA，VEGFB，VEGFC，FGF2，PGF

細(xì)胞骨架反應(yīng)：ACTA1、ACTA2、ACTB、ACTG1、ACTG2

附著力調(diào)節(jié)： ITGAV， ITGB1， ITGB3， ITGB5， PTK2

下游轉(zhuǎn)錄因子：ATF2、FOS、JUN、KRAS、NRAS

GeneQuery™ qPCR 芯片試劑盒采用 96 孔板格式的 qPCR 就緒，每個(gè)孔包含一個(gè)引物組，可識(shí)別并有效擴(kuò)增特定靶基因的 cDNA。精心設(shè)計(jì)的引物確保：（i）qPCR分析中的優(yōu)良退火溫度為65°C（含2 mM Mg2+且不含DMSO）;（ii）除非另有說明，否則引物集可識(shí)別靶基因的所有已知轉(zhuǎn)錄本變體;（iii）只有一個(gè)基因被擴(kuò)增。每個(gè)引物組都已通過qPCR和熔解曲線分析和凝膠電泳進(jìn)行了驗(yàn)證。

ScienCell's GeneQuery™ Human Signaling Pathway qPCR Array Kit (GQH-VEG) profiles 88 key genes involved in VEGF and VEGF-related signaling.  VEGF is a growth factor known for stimulating angiogenesis and vasculogenesis.  As such, it is integral to proper blood vasculature formation during development, maintenance, and wound healing.  Aberrant VEGF signaling is associated with ischemia, diabetic retinopathy, macular degeneration, and solid tumor progression.  Brief examples of how included genes may be grouped according to their function are shown below:

·         Signaling receptors: FLT1, FLT4, KDR, KIT, FGFR1

·         Growth factor ligands: VEGFA, VEGFB, VEGFC, FGF2, PGF

·         Cytoskeletal response: ACTA1, ACTA2, ACTB, ACTG1, ACTG2

·         Adhesion regulation: ITGAV, ITGB1, ITGB3, ITGB5, PTK2

·         Downstream transcription factors: ATF2, FOS, JUN, KRAS, NRAS

GeneQuery™ qPCR array kits are qPCR ready in a 96-well plate format, with each well containing one primer set that recognizes and efficiently amplifies a specific target gene's cDNA. The carefully designed primers ensure that: (i) the optimal annealing temperature in qPCR analysis is 65°C (with 2 mM Mg2+and no DMSO); (ii) the primer set recognizes all known transcript variants of the target gene, unless otherwise noted; and (iii) only one gene is amplified. Each primer set has been validated by qPCR with melt curve analysis and gel electrophoresis.

GeneQuery™ 人類 VEGF 信號(hào)通路 qPCR 陣列板布局*（8 個(gè)粗體和斜體對(duì)照）

提示：基因選擇可能會(huì)根據(jù)新的研究和開發(fā)進(jìn)行更新

ScienCell基因表達(dá)分析產(chǎn)品訂購信息：

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GK010   人類黑素細(xì)胞發(fā)育和色素沉著qPCR檢測試劑盒，Human Melanocyte Development & Pigmentation qPCR Array Kit

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GK013   人類星型膠質(zhì)細(xì)胞轉(zhuǎn)錄因子qPCR檢測試劑盒，Human Astrocyte Transcription Factors qPCR Array Kit

GK017   人血管生成qPCR檢測試劑盒，Human Angiogenesis qPCR Array Kit

GK018   人內(nèi)皮細(xì)胞表型異質(zhì)性qPCR檢測試劑盒，Human Endothelial Cell Phenotypic Heterogeneity qPCR Array Kit

GK019   人內(nèi)皮細(xì)胞生物學(xué)qPCR檢測試劑盒，Human Endothelial Cell Biology qPCR Array Kit

GK020   人B細(xì)胞受體信號(hào)通路qPCR檢測試劑盒，Human B Cell Receptor Signaling Pathway qPCR Array Kit

GK021   人類T細(xì)胞受體信號(hào)通路qPCR檢測試劑盒，Human T Cell Receptor Signaling Pathway qPCR Array Kit

GK022   人內(nèi)吞作用qPCR檢測試劑盒，Human Endocytosis qPCR Array Kit

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GK025   人類Notch信號(hào)通路qPCR檢測試劑盒，uman Notch Signaling Pathway qPCR Array Kit

GK026   人類Wnt信號(hào)通路qPCR檢測試劑盒，Human Wnt Signaling Pathway qPCR Array Kit

GK027   人類非經(jīng)典Wnt信號(hào)通路qPCR檢測試劑盒，Human Noncanonical Wnt Signaling Pathways qPCR Array Kit

GK028   人類Wnt信號(hào)靶基因qPCR檢測試劑盒，Human Wnt Signaling Target Genes qPCR Array Kit

GK029   Human Tie2/Angpt信號(hào)qPCR檢測試劑盒，Human Tie2/Angpt Signaling qPCR Array Kit

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GK040   人成纖維細(xì)胞生長因子信號(hào)通路qPCR檢測試劑盒，Human Fibroblast Growth Factor Signaling Pathway qPCR Array Kit

GK041   人體皮膚傷口愈合qPCR檢測試劑盒，Human Skin Wound Healing qPCR Array Kit

GK056   人體止血qPCR檢測試劑盒，Human Hemostasis qPCR Array Kit

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GK061   人類DNA損傷感應(yīng)qPCR檢測試劑盒，Human DNA Damage Sensing qPCR Array Kit

GK062   人類細(xì)胞生長和分裂qPCR檢測試劑盒，Human Cell Growth and Division qPCR Array Kit

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GK072   人類適應(yīng)性免疫反應(yīng)qPCR檢測試劑盒，Human Adaptive Immune Response qPCR Array Kit

GK073   人類小膠質(zhì)細(xì)胞Sensome qPCR檢測試劑盒，Human Microglial Sensome qPCR Array Kit

GK074   人角質(zhì)細(xì)胞生物學(xué)qPCR檢測試劑盒，Human Keratocyte Biology qPCR Array

GK078   人類神經(jīng)細(xì)胞生物學(xué)qPCR檢測試劑盒，Human Neuronal Cell Biology qPCR Array Kit

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GK081   人類周細(xì)胞生物學(xué)qPCR檢測試劑盒，Human Pericyte Biology qPCR Array Kit

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GK090   人體細(xì)胞連接qPCR檢測試劑盒，Human Cell Junctions qPCR Array Kit

GK091   人肝星狀細(xì)胞生物學(xué)qPCR檢測試劑盒，Human Hepatic Stellate Cell Biology qPCR Array Kit

GK092   人胰腺星狀細(xì)胞生物學(xué)qPCR檢測試劑盒，Human Pancreatic Stellate Cell Biology qPCR Array Kit

GK093   Human Renal Mesangial Cell Biology qPCR Array Kit，Human Renal Mesangial Cell Biology qPCR Array Kit

GK094   Human Mesenchymal Stem Cell Differentiation qPCR Array，Human Mesenchymal Stem Cell Differentiation qPCR Array Kit

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GK099   人類骨骼肌細(xì)胞生物學(xué)qPCR檢測試劑盒，Human Skeletal Muscle Cell Biology qPCR Array Kit

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