GK087 ScienCell 人類染色質組織和重塑qPCR檢測試劑盒，Human Chromatin Organization and Remodeling qPCR Array Kit

ScienCell 研究實驗室（ScienCell）是一家生物技術公司，其使命是實驗和治療用細胞和細胞相關產品的研究和發(fā)展。 ScienCell為研究界提供各種高質量的正常的人類和動物細胞，細胞培養(yǎng)基和試劑，培養(yǎng)基添加因子，細胞來源的RNA，cDNA和蛋白質。ScienCell的科學家們以改善生活質量，實現(xiàn)細胞的能力，打擊人類退化性疾病為目的研究和開發(fā)各種細胞治療策略。ScienCell總部設在美國加利福尼亞州圣地亞哥，公司成立于1999年。

北京諾博萊德作為ScienCell品牌的經(jīng)銷商，為客戶提供，正規(guī)進口，貨期穩(wěn)定，折扣好的服務標準。

GK087 ScienCell人類染色質組織和重塑qPCR檢測試劑盒，Human Chromatin Organization and Remodeling qPCR Array Kit，產品簡介：

產品品牌： ScienCell

產品貨號：GK087

產品名稱：GK087 ScienCell人類染色質組織和重塑qPCR檢測試劑盒，Human Chromatin Organization and Remodeling qPCR Array Kit

產品規(guī)格：One 96-well plate, one 20ul reaction per well

GK087 ScienCell人類染色質組織和重塑qPCR檢測試劑盒，Human Chromatin Organization and Remodeling qPCR Array Kit， 產品說明：

ScienCell的GeneQuery™人類染色質組織和重塑qPCR陣列試劑盒（GQH-CHM）分析了88個參與調節(jié)染色質結構的關鍵基因。 染色質壓縮DNA，允許有絲分裂，同時防止DNA損傷和控制基因表達。 它是一種復雜的大分子，僅在由RNA，DNA和蛋白質組成的真核生物中發(fā)現(xiàn)。 染色質的基本蛋白質是組蛋白，組蛋白修飾有助于改變染色質堆積和結構。 如何根據(jù)其功能對所包含的基因進行分組的簡要示例如下所示：

染色質重塑：ATRX，CBX2，CREBBP，EP300，MECOM

染色質組織：HIST1H3A，HIST1H3J，HIST2H3A，HIST2H3D，HIST3H3

組蛋白乙?；?span>/去乙?；?span>ELP3、HDAC1、HDAC4、JADE2、KAT6A

組蛋白甲基化/去甲基化：DNMT3A、DOT1L、EZH2、JMJD6、KDM6A

GeneQuery™ qPCR 芯片試劑盒采用 96 孔板格式的 qPCR 就緒，每個孔包含一個引物組，可識別并有效擴增特定靶基因的 cDNA。精心設計的引物確保：（i）qPCR分析中的優(yōu)良退火溫度為65°C（含2 mM Mg2+且不含DMSO）;（ii）除非另有說明，否則引物集可識別靶基因的所有已知轉錄本變體;（iii）只有一個基因被擴增。每個引物組都已通過qPCR和熔解曲線分析和凝膠電泳進行了驗證。

ScienCell's GeneQuery™ Human Chromatin Organization and Remodeling qPCR Array Kit (GQH-CHM) profiles 88 key genes involved in regulating chromatin structure.  Chromatin compacts DNA, allowing mitosis while preventing DNA damage and controlling gene expression.  It is a complex macromolecule that is only found in eukaryotes consisting of RNA, DNA, and protein.  The basic proteins of chromatin are histones and histone modifications contribute to altering chromatin packing and structure.  Brief examples of how included genes may be grouped according to their function are shown below:

·         Chromatin remodeling: ATRX, CBX2, CREBBP, EP300, MECOM

·         Chromatin organization: HIST1H3A, HIST1H3J, HIST2H3A, HIST2H3D, HIST3H3

·         Histone acetylation/deacetylation: ELP3, HDAC1, HDAC4, JADE2, KAT6A

·         Histone methylation/demethylation: DNMT3A, DOT1L, EZH2, JMJD6, KDM6A

GeneQuery™ qPCR array kits are qPCR ready in a 96-well plate format, with each well containing one primer set that recognizes and efficiently amplifies a specific target gene's cDNA. The carefully designed primers ensure that: (i) the optimal annealing temperature in qPCR analysis is 65°C (with 2 mM Mg2+and no DMSO); (ii) the primer set recognizes all known transcript variants of the target gene, unless otherwise noted; and (iii) only one gene is amplified. Each primer set has been validated by qPCR with melt curve analysis and gel electrophoresis.

GeneQuery™ 人類染色質組織和重塑 qPCR 陣列板布局*（8 個粗體和斜體對照）

提示：基因選擇可能會根據(jù)新的研究和開發(fā)進行更新

ScienCell基因表達分析產品訂購信息：

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